Tennis players at every level face distinctive musculoskeletal challenges arising from explosive serves, rapid multidirectional movement, and repetitive overhead mechanics. This authoritative volume delivers a comprehensive integrative biomedical framework for understanding, preventing, and managing tennis-related trauma. It synthesizes extensive epidemiological data, sport-specific biomechanical mechanisms, and current knowledge of tissue injury and healing with detailed coverage of both conventional treatments and pioneering regenerative strategies. Key topics include injury classification and mechanisms, intrinsic and extrinsic risk factors, clinical assessment and imaging, platelet-rich plasma applications, mesenchymal stem cell therapies, peptide-based interventions, mitochondrial dynamics in recovery, and advanced physiotherapeutic modalities such as hyperbaric oxygen therapy. The text further addresses phased rehabilitation protocols, functional and performance testing, return-to-play decision-making, and comorbidity considerations. Bridging traditional sports medicine with emerging cellular and molecular approaches, this resource equips competitive players, coaches, physiotherapists, sports physicians, and researchers with evidence-based knowledge to optimize recovery, reduce reinjury risk, and support long-term participation in the sport.