Crohn’s Disease

This presentation delivers a comprehensive exploration of Crohn’s Disease—a chronic, relapsing inflammatory bowel disorder that can affect any part of the gastrointestinal tract, leading to abdominal pain, diarrhea, weight loss, malnutrition, and systemic complications. It examines the epidemiology, genetic predispositions (e.g., NOD2 mutations), environmental risk factors, and key pathogenic mechanisms, including dysregulated immune responses, intestinal barrier dysfunction, microbial dysbiosis, and persistent inflammation. Extraintestinal manifestations such as arthritis, skin disorders, and ocular involvement are also discussed.

Diagnostic strategies include endoscopy, imaging, histopathology, and biomarkers such as fecal calprotectin, while conventional treatment ranges from corticosteroids, immunosuppressants, and biologics to surgical intervention in refractory cases. Beyond established therapies, this presentation introduces advanced regenerative and integrative innovations, including Precursor Stem Cell Therapy (PSCT), Autologous Active Specific Immunotherapy (AASI®), Nano Organo Peptides (NOP) Thymus and Mito Organelle (MO) Thymus for Thymus Therapy, Nano Organo Peptides (NOP) Super Transfer Factor (STF), Mito Organelles (MO) Super Transfer Factor (STF), and GcMAF Forte. Supported by scientific references and case-based insights, this program is tailored for gastroenterologists, immunologists, and healthcare professionals seeking deeper expertise in Crohn’s pathogenesis and emerging therapeutic frontiers.