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Modulation of Cellular Senescence in HEK293 and HepG2 Cellsby Ultrafiltrates UPla and ULu Is Partly Mediated by Modulation of Mitochondrial Homeostasis under Oxidative Stress

Authors: Junxian Zhou, Kang Liu, Chris Bauer, Gerald Bendner, Heike Dietrich, Jakub Peter Slivka, Michael Wink, Michelle B. F. Wong, Mike K. S. Chan and Thomas Skutella

Publisher:  MDPI, 4 April 2023, Int. J. Mol. Sci. 2023, 24(7), 6748

Publisher URL:  https://www.mdpi.com/1422-0067/24/7/6748

36 Downloads

Autism Spectrum Disorder: Bioregenerative Medicine with Stem Cell Therapy

Author: Prof. Dr. Mike K.S. Chan, Prof. Dr. Yuriy Nalapko, Dr. Svetlana Yartseva and Prof. Dr. Michelle B.F. Wong
Published by: EUROPEAN WELLNESS ACADEMY
Medical Research: ISBN: 9781662930034, eISBN: 9781662927492
Library of Congress Control Number: 2022941474

Autism Spectrum Disorder: Bioregenerative Medicine with Stem Cell Therapy is intended for a wide audience: parents of autistic children, regular and special education teachers, medical specialists, and for everybody who wants to learn about modern approaches to treat developmental diseases. This comprehensive monograph contains broad knowledge starting with a brief history of autism spectrum disorder, theories of occurrence and diagnosis, and reviewing modern behavioural, pharmacological, and bioregenerative therapeutic technologies.

Why is this book different? It is grounded in recent data related to new conceptualizations of the occurrence of autism spectrum disorder which consider autism a mitochondrial disease. Thus, the authors explain core concepts. What is a mitochondrion? How does its damage appear and correlate to the signs and symptoms of autism? What kind of bioregenerative therapies have great therapeutic potential? Almost all therapeutic methods for autism spectrum disorder are discussed from the point of view of the evidence based medicine.

Bioregenerative technology is based on the restoration of damaged subcellular structures like mitochondria and brain cell peptides. Bioregenerative antioxidant therapy, hyperbaric oxygen therapy, transcranial magnetic/direct current stimulation, and mitochondrial organelles replacement therapy are key directions in the treatment of autism spectrum disorder.

Finally, new technology that holds high potential for the restoration of brain function is discussed—bioregenerative stem cell therapy. Because of the strong correlation between the symptoms of autism and changes in the brain, physicians have great tools to regulate such clinical symptoms through stem cell therapy. Most importantly, the authors have personal experience using the stem cell therapy with autism spectrum disorder patients. All facts are strongly supported by published scientific reviews and trials.

Prof. Dato’ Sri Dr. Mike K.S. Chan is an author, educator and pioneer of Organotherapy, Cellular Therapy and Cell Membrane Therapy in Europe and Asia since the early 1980s. He founded and funded one of the world’s largest research on Bio-Molecular and Bio-Regenerative Medicine in Switzerland and Germany, with a global presence in almost eighty countries. He has conducted more than 1,000 lectures, seminars, and symposiums worldwide in the fields of organotherapy, cell therapies, age reversal, regenerative medicine, and stem-cell therapies.

Dr. Yuriy Nalapko, MD, PhD, is an academician and practical medical doctor in Intensive Care, Antiaging, and Bioregenerative Medicine. An area of scientific interest is longevity and how a cell functions with different diseases. He is the author of many handbooks, monographs, and more than 300 articles. Based on his clinical experience, he proposed new approaches to reverse degenerative diseases of the brain, liver, and endocrine organs in different disorders. In Metabolic Disorder Therapy, he combines preventive, pharmacological, and bioregenerative approaches as a state-of-the-art paradigm to correct structural and functional malfunctions.

Dr. Svetlana Yartseva, MD, PhD, is a certified Endocrinologist and Internal Diseases Practitioner. A member of several international associations on the study of diabetes; the European Thyroid Association; and the European Association of Preventive, Regenerative, and Antiaging Medicine; she is a Consultant at numerous private clinics. Her main concern is treatment of patients with obesity, metabolic syndrome, and diabetes mellitus through modern pharmacological and non-pharmacological methods.

Prof. Dato' Sri Dr. Michelle B.F. Wong, ND, PhD is a scientist, researcher and educator actively involved in research and development (R&D) work on stem cells focusing on Fetal Precursor Stem-Cell Therapy. She is the Co-Founder/Senior Technical Advisor and Researcher in FCTI Inc., specialising in Stem cell Research and Bio-Regenerative Medicine for more than three decades. A prominent speaker, Michelle Wong presents at educational programs and global conferences on stem cells, cell therapy and biological medicine for physicians and healthcare practitioners worldwide.

Price: $75.00 – $120.00
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Active Specific Immunotherapy: mechanisms of Action and Clinical Applications in Bioregenerative and Anti-aging Medicine, Autoimmune Conditions and Cancers

Authors: Mike KS Chan, Michelle BF Wong, Roni Moya, Dmytro Klokol, Shing Yi Pan

Publisher: MedCrave Group, International Journal of Vaccines & Vaccination, Volume 7 Issue 1 - 2023

Publisher URL: http://medcraveonline.com/IJVV/active-specific-immunotherapy-mechanisms-of-action-and-clinical-applications-in-bioregenerative-and-anti-aging-medicine-autoimmune-conditions-and-cancers.html

38 Downloads

The Role of Mitochondria in Cartilage Degenerative Disorders

Authors: Yuriy Nalapko, Jonathan R. T. Lakey, Orn Adalsteinsson, Dmytro Klokol, Thomas Skutella, Shing Yi Pan, Augusta Wellington, Michelle B. F. Wong, Mike K. S. Chan and Desiree Cox

Publisher:  International Journal of Biomedical Research & Practice, ISSN 2769-6294, Volume 2 | Issue 1

37 Downloads

Protective Effects of Stem Cell-Derived Peptides in Preventing Autoimmune Diabetes in the Non-Diabetic Mouse Model

Authors: Jonathan RT Lakey, Alicia Wells, Adam Good, Kimia Damyar, Tori R Tucker, Yuriy Nalapko, Dmytro Klokol, Michelle B.F. Wong, Michael Alexander, Mike K.S. Chan and Desiree C.T. Cox

Publisher:  American Journal of Biomedical Science & Research, ISSN: 2642-1747, June 29, 2022

Publisher URL: http://dx.doi.org/10.34297/AJBSR.2022.16.002264

38 Downloads

Mass Spectrometry Analysis of Novel Stem Cell-Derived Peptides

Authors: Alicia Wells, Adam Good, Kimia Damyar, Michael Alexander, Ben Katz, Michael KS Chen, Michelle BF Wong, Desiree Cox, Dmytro Klokol and Jonathan RT Lakey

Publisher:  American Journal of Biomedical Science & Research, ISSN: 2642-1747, May 20, 2022

Publisher URL: http://dx.doi.org/10.34297/AJBSR.2022.16.002215

34 Downloads

Autism Spectrum Disorder, Integrative Approach

By Prof. Dr. Mike K.S. Chan and Dr. Dina Tulina
Published by: EUROPEAN WELLNESS ACADEMY
Medical Research: ISBN: 9781662930126, eISBN: 9781662930133
Library of Congress Control Number: 2022941487

Autism is a mental and psychological developmental disorder with a pronounced deficit in emotional and communication skills. The word ‘Autism’ is defined as a person being withdrawn into themselves. A person with autism spectrum disorder never expresses their emotions, fails to gesture or speak to others, and their behaviour often lacks social meaning. Many parents are concerned about how to recognise their child has autism and at what age the condition first manifests.

Written in accessible language for parents of patients as well as medical staff, this book provides tests for identifying autism without medical training. The symptoms which constitute Autism Spectrum Disorder are described at great length. The approach to the individual's condition is important. Autism is not an illness or even a diagnosis—it is a state of mind in which a person is ensconced in their own world. This book is based on an understanding of the person's condition, offering comprehensive, holistic help to improve the condition and help the individual socialise and integrate into society.

Parents of children diagnosed with autism often ask their doctor—can the condition be cured? There is no cure for autism, but by using corrective methods, it is possible to significantly improve the person with autism state and help them adapt to the world as much as possible. Of course, parents must work closely with educators, medical providers, and routines over a long period of time but the results of these efforts can be monumental. Autism is not a sentence, it is a story.

Professor Dato’ Sri Dr. Mike K.S. Chan is a pioneer of Cellular and Cell Membrane Therapy in Europe and Asia since the early 1980’s. He founded one of the world’s largest researchers of Bio-Molecular Medicine based in Switzerland and Germany with a global presence in almost eighty countries. He has conducted more than 1,000 lectures, seminars, and symposiums worldwide in the fields of antiaging, cell regeneration, regenerative medicine, and stem-cell therapies.

Dr. Dina Tulina is a specialist in anti-aging and regenerative medicine with extensive experience in the field. Basing her knowledge on scientific and research experience within the scope of neuropsychiatry (age-related brain changes and associated cognitive and mental disorders), Dr Dina has expanded and enriched her expertise by incorporating preventative medicine, natural and complementary therapies for age-related changes, and the use of biologics in regenerative medicine. Guided by the philosophy "He, who owns the youth, owns the future", Dr Dina is deeply passionate about the educational aspects of anti-aging medicine and wellness.

Price: $55.00 – $110.00
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Maldi-Tof Analysis of Mitochondrial Peptides

Authors: Adam Good, Alicia Wells, Ben Katz, Michael Alexander, Dmytro Klokol, Mike K.S. Chan, Michelle B.F. Wong, Desiree C.T. Cox, Jonathan R.T. Lakey

Publisher: Clinical Medicine Insights, ISSN (O) 2694-4626, 8 June 2022, CMI 03 (02), 297−303 (2022)

Publisher URL: https://medicineinsights.info/index.php/cmi/article/view/142

113 Downloads

Transfer Factors: Properties, Mechanism Of Action And Its Clinical Applications

By Prof Dr Mike KS Chan, Prof. Dr. Michelle B.F. Wong, Dr Patricia Pan, Dr Dina Tulina, Yvonne Chia, Clarice EA, Yee Hui Rong and Yenny Kenisi.
Published by EUROPEAN WELLNESS ACADEMY – Medical Research: ISBN: 9781662930010, eISBN: 9781662930027
Library of Congress Control Number: 2022941736

To date, transfer factors hold promise as one of the most exciting discovery in immunology and disease prevention. As the 21st century unfolds, these small molecules represent an important key to human health and well-being. Transfer factors are material present in dialysable leukocyte extracts capable of transferring cell-mediated immunity to pathogens. Transfer factors from one immune donor can be introduced into a non-immune recipient, potentially delivering an improved ability to fight threats to the recipient’s health. Similar to vaccines, transfer factors are prophylactic when administered prior to exposure to a pathogen.

This book is an overview of basic immunology and the concept of transfer factors derived from past and current scientific publications. In this book, the properties, mechanism of action, and clinical applications of transfer factors are described. Since their discovery, evidence suggests transfer factors play an important role as immune modulators in treating diseases associated with the defective function of cell-mediated immunity such as cancer, infectious diseases, etc.

The MF Plus Super Transfer Factor is then introduced including its function, characteristics, course, mode of administration, and advantages. The conclusion compiles research papers of transfer factor from years 2009 to 2020.

This book will interest researchers and scientists in fields such as immunology, molecular medicine, biomedicine, immunotherapy, pathology, microbiology, and oncology.

Price: $49.00 – $89.00
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A Compilation of Cellular and Tissue Xenotransplantation Studies (1838-2022): A Promising Approach for the Treatment of Diseases

By Prof Dr Mike KS Chan, Prof. Dr. Michelle B.F. Wong, Dr Patricia Pan, Yvonne Chia, Clarice EA, Yee Hui Rong and Yenny Kenisi
Published by EUROPEAN WELLNESS ACADEMY – Medical Research: ISBN: 9781662930041, eISBN: 9781662928574
Library of Congress Control Number: 2022941169

The success of transplantation to treat human diseases has greatly increased the demand for organs and tissues. Xenotransplantation, the use of animals as donors, is viewed increasingly as a solution to this problem. The pig-to-NHP model has become the standard for preclinical studies of cell and tissue xenotransplantation prior to starting a clinical trial.

This is A Compilation of Cell and Tissue Xenotransplantation Studies (1838-2022): A Promising Approach for the Treatment of Diseases and a collection of reminiscences by surgeons and scientists who made significant research contributions toward achieving successful transplantation of animal cells and tissues into humans. It records the works of the world’s leading researchers in this field which will impact the future medical care of patients with diabetes, liver failure, neurodegenerative disorders, corneal blindness, etc.

It also provides a comprehensive overview of applications of cellular and tissue xenotransplantation for a range of diseases especially those that result from tissue loss or dysfunction. The importance of the decellularization technique in animal tissues and organs as implantable biomaterials in the field of regenerative medicine and tissue engineering is also highlighted.

Essential reading for physicians, scientists, and lay persons with an interest in xenotransplantation; those caring for patients with life-threatening diseases; and also those interested in understanding the potential of genetic and tissue engineering in science and medicine. This book charts a historical record of the research which has contributed to the advancement of medicine called “the next great medical revolution.” Many believe we are on the threshold of clinical trials using genetically modified animals as organ donors. If successful, the benefits of clinical xenotransplantation will be enormous and will represent one of the greatest advances in modern medicine.

Price: $39.50 – $79.00
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