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Restoring Immune Balance and Intestinal Integrity in Crohn’s Disease: A Framework for Targeted Regenerative and Immunomodulatory Therapies

A new scientific review just published in the American Journal of Biomedical Science & Research explores a fresh approach to managing Crohn’s Disease – by focusing on restoring immune balance and repairing gut integrity from the inside out.

Led by experts from European Wellness – including Prof. Dato’ Sri Dr. Mike Chan, Prof. Dato’ Sri Dr. Michelle Wong, and Prof. Dr. Dmytro Klokol – alongside collaborators from UC Irvine and GATC Health Inc, this review lays the foundation for a more targeted, potentially more holistic path forward in this field.

What their research helped uncover:
🔹 Advanced cell-based approaches, like organoid and stem cell therapies, may help rebuild damaged gut lining
🔹 Peptide-powered strategies may reduce inflammation, support healing, and bring precision to immune regulation
🔹 Tolerogenic immune training – an approach that could potentially teach the immune system to stop overreacting without suppressing it entirely
🔹 A combined framework that aims to go beyond symptoms by addressing root imbalances

Research is still in early stages – but the possibilities are definitely worth exploring. This research could signal a promising shift for patients living with IBD worldwide.

Restoring Immune Balance and Intestinal Integrity in Crohn’s Disease: A Framework for Targeted Regenerative and Immunomodulatory Therapies

by

Prof. Dr. Mike K.S. Chan, Ian Jenkins, Prof. Dr. Michelle B.F. Wong, Krista Casazza, Dr. Dmytro Klokol and Jonathan R.T. Lakey

American Journal of Biomedical Science & Research; 27(4), 2025
https://biomedgrid.com/pdf/AJBSR.MS.ID.003587.pdf

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