Cell Therapy – Cellular & Tissue Xenotransplantation: Challenges, Progress & Current Applications
$25.00 – $50.00
CELL THERAPY – CELLULAR & TISSUE XENOTRANSPLANTATION: Challenges, Progress and Current Applications. The team of researchers who collaborated with Dr. Chan, pioneer of these studies, has produced a document with a strong bibliographic depth for those who wish to explore the content.
As we read in the preface: “For more than a century, xenotransplantation has been viewed as a potential solution to address the scarcity of human organs and tissue which are available for allotransplantation.
However, due to numerous obstacles, including immunological rejection, regulatory restrictions, and ethical considerations; the progress of xenotransplantation has been stagnant and largely trapped in the preclinical stage. This book explores the challenges surrounding the field of xenotransplantation, looks into possible strategies to overcome them and discusses the potential and future of this field”.
Description
Author
Prof Dr Mike KS Chan, Prof Dr Michelle Wong, Dr Patricia Pan, Dr Roni Lara Moya, Prof Dr Thomas Skutella, Chen Rui, Sabine Conrad, Yvonne Chia, Clarice EA, Yee Hui Rong and Yenny Kenisi.
Published by
EUROPE BOOKS, UK
ISBN: 9791220146456
Author Bio:
Prof. Dato’ Sri Dr. Mike K.S. Chan is an author, educator and pioneer of Organotherapy, Cellular Therapy and Cell Membrane Therapy in Europe and Asia since the early 1980s. He founded and funded one of the world’s largest research on Bio-Molecular and Bio-Regenerative Medicine in Switzerland and Germany, with a global presence in almost eighty countries. He has conducted more than 1,000 lectures, seminars, and symposiums worldwide in the fields of organotherapy, cell therapies, age reversal, regenerative medicine, and stem-cell therapies.
Prof. Dato Sri Dr. Michelle B.F. Wong, ND, PhD is a scientist, researcher and educator actively involved in research and development (R&D) work on stem cells focusing on Fetal Precursor Stem-Cell Therapy. She is the Co-Founder/Senior Technical Advisor and Researcher in FCTI Inc., specializing in Stem cell Research and Bio-Regenerative Medicine for more than three decades. A prominent speaker, Michelle Wong presents at educational programs and global conferences on stem cells, cell therapy and biological medicine for physicians and healthcare practitioners worldwide.
Table of Content
| PREFACE | ix |
| ABBREVIATIONS | xi |
| CHAPTER 1: AN OVERVIEW OF XENOTRANSPLANTATION | 1 |
| Introduction | 1 |
| The Rationale of Xenotransplantation | 2 |
| Categories of Xenotransplantation . | 3 |
| Xenotransplantation – The Progress Since 1800 | 5 |
| Xenogeneic Cell Therapy in Regenerative Medicine | 9 |
| CHAPTER 2: THE CHALLENGES OF XENOTRANSPLANTATION AND STRATEGIES TO OVERCOME THEM | 11 |
| Introduction | 11 |
| The Hurdles of Xenotransplantation | 12 |
| Immunological Barriers | 13 |
| Infectious Disease Risks | 20 |
| Strategies to Overcome the Hurdles of Xenotransplantation | 23 |
| Overcoming Immunogenicity and Rejection | 24 |
| Similarity Between Human and Animals of Different Species | 36 |
| Source Animal Characterization | 43 |
| Conclusion | 44 |
| CHAPTER 3: ETHICS AND REGULATIONS IN XENOTRANSPLANTATION | 46 |
| Introduction | 46 |
| Ethical Issues and Religious Views | 46 |
| Regulatory Approaches on Xenotransplantation | 48 |
| International Xenotransplantation Association | 49 |
| Regulation in the US | 50 |
| Regulation in the UK and Europe | 51 |
| Regulation in the Japan | 53 |
| Regulation in the China | 54 |
| Regulation in the South Korea | 54 |
| Regulation in the Australia | 55 |
| Conclusion | 55 |
| CHAPTER 4: THE POTENTIAL OF CELL THERAPY – CELLULAR AND TISSUE XENOTRANSPLANTATION | 56 |
| Introduction | 56 |
| Clinical Potential of Cell Therapy – Cellular and Tissue Xenotransplantation | 57 |
| Organ Reconstruction | 58 |
| Tissue Defects | 59 |
| Clinical Cellular and Tissue Xenotransplantation | 60 |
| Xenogeneic Cell Therapy and Autoimmune Tolerance | 61 |
| Advantages of Xenogeneic Cell Therapy | 66 |
| Conclusion | 69 |
| CHAPTER 5: FUTURE DIRECTION OF XENOTRANSPLANTATION | 70 |
| CHAPTER 6: CONCLUDING REMARKS | 77 |
| BIBLIOGRAPHY | 78 |
Additional information
| Weight | N/A |
|---|---|
| Select Book Type | Printed English (Softcover), eBook English |
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