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Peptide-Based Precision Therapeutics for Cardiac Disease: Targeting Mitochondrial Dysfunction, Fibrosis, and Inflammation

Authored by an international team that includes European Wellness experts Prof. Dato’ Sri Dr. Mike Chan, Prof. Dato’ Sri Dr. Michelle Wong, Prof. Dr. Dmytro Klokol and Prof. Dr. Olha Nishkumai alongside researchers from the University of California, Irvine (UCI), the study explores advanced peptide therapeutics that specifically target mitochondrial dysfunction, fibrosis, and inflammation – 3 critical factors in cardiac disease.

Here’s why this research is exciting…
🔹 Peptides can be engineered to reach specific cells and organelles in the heart, potentially reducing side effects compared to traditional treatments.
🔹 Preclinical trials show potential in repairing damaged heart tissue, reducing inflammation, and improving cardiac function.
🔹 Novel peptide systems like NOPs (nano-organo peptides) and MTPs (mitochondria-targeted peptides) may help fine-tune treatment like never before.

Research continues – but this could be a major step toward a new kind of precision therapy for one of the world’s biggest health challenges! 💡

Peptide-Based Precision Therapeutics for Cardiac Disease: Targeting Mitochondrial Dysfunction, Fibrosis, and Inflammation

by

Prof. Dr. Mike K.S. Chan, Prof. Dr. Michelle B.F. Wong, Krista Casazza, Dr. Dmytro Klokol, Dr. Olha Nishkumai, Michael Alexander and Jonathan R.T. Lakey

American Journal of Biomedical Science & Research; 27(3), 2025
https://biomedgrid.com/pdf/AJBSR.MS.ID.003560.pdf

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