Stargardt Disease

This presentation provides a detailed overview of Stargardt disease, an inherited macular disorder that causes progressive central vision loss, particularly in children and young adults. It explains ABCA4 gene mutations, autosomal recessive inheritance, toxic lipofuscin accumulation, retinal pigment epithelium dysfunction, and subsequent photoreceptor degeneration. Clinical features, disease classification, diagnostic methods, complications, prognosis, and emerging pharmacological, gene, and stem cell therapies are also discussed. A major section focuses on regenerative and biomolecular approaches, including precursor stem cell therapy, mitochondria-targeted peptides, nano organo peptides, and ocular peptide formulations intended to support retinal cells, optic nerve function, cellular energy, and tissue repair.