(Day 2): Powering Cells, Extending Life: NAD and Klotho Take Center Stage at PAAAMMI 2025

MANILA, (Sept 7, 2025) – The second day of the 13th Annual PAAAMMI Convention shifted focus from aesthetic rejuvenation to the science of longevity, spotlighting two molecular players that could redefine how humans age: NAD+ and the Klotho protein.

Dr. Glen K. Alvin, of the European Wellness Biomedical Group, led the session “NAD & the Next Scientific Innovation, Klotho Protein Extract into Longevity Medicine.” He described NAD+ as the cell’s essential energy source and Klotho as a genetic regulator often linked to lifespan.

“NAD fuels the energy of our cells, while Klotho orchestrates how we age,” Alvin told delegates. “By restoring both, we can shift health care from treating decline to proactively supporting longevity.”

Delegates heard how NAD+ restoration therapies are being studied for their role in boosting metabolism, cognitive function, and recovery, while Klotho protein interventions show promise in slowing cardiovascular decline and reducing age-related deterioration.

Adding weight to the discussion, Prof. Dato’ Sri Dr. Mike Chan underscored why these molecules matter within the wider regenerative field:

“NAD and Klotho represent more than theory, they are evidence that aging can be targeted at its root causes,” Chan said. “When we integrate these pathways into clinical practice, we are no longer just managing age—we are redefining it.”

The Day 2 program concluded the two-day convention under the theme “Regenerative Aesthetics Redefined: The New Age of Longevity.” Organizers said the discussion on NAD and Klotho pointed to a future where regenerative medicine bridges both appearance and healthspan, offering patients not just years to their life, but life to their years.

With NAD and Klotho now entering clinical conversations, PAAAMMI 2025 made clear that regenerative medicine is moving from the realm of aspiration to active practice, reshaping how people look, feel, and live.

🔑 Key Takeaways – Day 2 at PAAAMMI 2025

Theme: “Regenerative Aesthetics Redefined: The New Age of Longevity”

From Aesthetics to Longevity

Day 2 shifted the spotlight from cosmetic rejuvenation to molecules that influence aging at its root, showing how science can extend not just years of life, but the quality of life.

NAD+: The Cellular Power Source

Dr. Glen Alvin explained how NAD+ fuels the body’s cells, improving metabolism, cognitive performance, and recovery. Restoring NAD+ levels offers a pathway to slow down age-related decline.

Klotho: The Longevity Protein

Alvin also introduced Klotho protein extract, often called the “longevity gene,” which has been linked to reduced cardiovascular risks and improved survival outcomes.

Prof. Mike Chan’s Perspective

Prof. Chan underscored why NAD+ and Klotho matter in the broader field of regenerative medicine:

“NAD and Klotho represent more than theory — they are evidence that aging can be targeted at its root causes.”

Bridging Beauty and Healthspan

Day 2 emphasized that regenerative medicine is no longer limited to aesthetics; it is becoming an integrated approach to health, vitality, and longevity.

Vision & Mission

• Vision: Deliver world-class care in wellness and
• Mission: Advance early detection, prevention, and reversal of age-related decline through evidence-based medicine.

European Wellness

Beyond the lectures, European Wellness Biomedical Group drew strong interest on the exhibition floor, showcasing its flagship innovations MF3 and MF Plus, along with an ecosystem of research-led wellness solutions.

Organisers said the 13th edition marked a turning point for the Academy: from aesthetics rooted in cosmetic results to a broader, evidence-based paradigm of regeneration, prevention, and longevity.

About PAAAMMI

The Philippine Academy of Aesthetic and Age Management Medicine Inc. (PAAAMMI) is a non-profit professional society that unites experts across dermatology, geriatrics, surgery, internal medicine, and allied disciplines. Its mission is to provide world-class care rooted in early detection, prevention, and age-related reversal using evidence-based medicine.

As the 13th PAAAMMI Annual Convention drew to a close, one message stood out clearly: the future of aesthetics is inseparable from longevity science. By shifting the conversation from surface-level treatments to cellular regeneration, prevention, and evidence-based standards, the event reaffirmed its role as the premier platform for advancing aesthetic and age-management medicine in the Philippines and beyond.

For PAAAMMI, the mission remains clear, to unite practitioners across disciplines, raise the bar of clinical practice, and empower patients with therapies that are not only innovative, but also safe, ethical, and life-changing.

As Prof. Mike Chan reminded delegates:

“Longevity is not about living forever. It is about living well.”

That vision, of beauty grounded in health and vitality — is what continues to make PAAAMMI a defining voice in the global conversation on regenerative aesthetics.

Prof. Chan welcomes visitors to the EW booth, underscoring the importance of evidence-based therapies in advancing patient care.

Celebrating global collaboration: Day 2 wraps up with smiles and camaraderie as leaders and experts pose together, symbolizing the shared mission of redefining aesthetics and longevity medicine.