Insomnia: Integrative Approaches to Longevity & Regenerative Medicine
Price range: $68.00 through $136.00
Sleep is a fundamental biological function essential for physical and mental well-being. It is critical in memory consolidation, tissue repair, immune system regulation, and metabolic balance, contributing to an increased risk of cardiovascular disease, obesity, diabetes, neurodegenerative disorders and premature ageing. Sleep disorders—especially insomnia—affect millions worldwide, leading to profound consequences on daily life and long-term health. Insomnia, characterised by difficulty falling asleep, staying asleep, or waking too early, is more than an inconvenience. Modern lifestyles have exacerbated sleep problems, with artificial light exposure, increased screen time, and 24-hour work cycles disrupting natural circadian rhythms. These factors, combined with psychological stress, anxiety, and poor sleep hygiene, have led to an epidemic of sleep disturbances. Social jetlag—where biological clocks are misaligned with modern schedules—is particularly common in adolescents and professionals, worsening insomnia and leading to long-term health consequences. The book explores how technology, societal pressures, and environmental influences have reshaped sleep patterns and how individuals can restore balance through targeted interventions.
This book presents an integrative approach, combining evidence-based lifestyle modifications, cognitive-behavioral therapies, and biological interventions to offer sustainable solutions for sleep improvement. One of the key focuses of this book is the intersection of sleep science with regenerative medicine. Cutting-edge research highlights the role of cellular repair, neuroprotection, and overall vitality. The book also discusses the latest advancements in sleep-enhancing therapies, including nutraceuticals, peptide treatments, and biohacking strategies aimed at improving sleep architecture and circadian alignment.
By exploring the science behind insomnia and offering practical, integrative solutions, this book serves as a valuable resource for anyone seeking to improve their sleep quality and overall health. Whether you are a healthcare professional, researcher, or someone struggling with sleep disturbances, you will find the tools and insights to reclaim restorative sleep and enhance longevity in this book.
Description
Authors
Prof. Dr. Mike K.S. Chan and Dr. Dina Tulina
Published by
EUROPEAN WELLNESS ACADEMY – Medical Research
Medical Research
ISBN: 9781662964947
eISBN: 9781662964954
Library of Congress Control Number: 2025939690
DOI: https://doi.org/10.69669/sl2184
Author Bio:
Professor Dato’ Sri Dr. Mike K.S. Chan is a pioneer of Cellular and Cell Membrane Therapy in Europe and Asia since the early 1980’s. He founded one of the world’s largest researchers of Bio-Molecular Medicine based in Switzerland and Germany with a global presence in almost eighty countries. He has conducted more than 1,000 lectures, seminars, and symposiums worldwide in the fields of antiaging, cell regeneration, regenerative medicine, and stem-cell therapies.
Dr Dina Tulina is a specialist in anti-aging and regenerative medicine with extensive experience in the field. Basing her knowledge on scientific and research experience within the scope of neuropsychiatry (age-related brain changes and associated cognitive and mental disorders), Dr Dina has expanded and enriched her expertise by incorporating preventative medicine, natural and complementary therapies for age-related changes, and the use of biologics in regenerative medicine. Guided by the philosophy “He, who owns the youth, owns the future”, Dr Dina is deeply passionate about the educational aspects of anti-aging medicine and wellness.
Table of Content
INTRODUCTION | 1 |
CHAPTER I: NORMAL SLEEP | 5 |
Why Is it Necessary for Humans to Sleep? | 7 |
Genetics of Sleep | 14 |
Sleep, Learning, and Memory | 20 |
Effects of Sleep Deprivation on Risk of Diseases | 24 |
Sleep Duration and Obesity | 29 |
Sleep Deprivation and Its Link to Type 2 Diabetes | 30 |
Sleep Deprivation, Heart Disease, and Hypertension | 33 |
Sleep Deprivation and Mood Disorders | 36 |
The Role of Sleep in Immune Function and Infection Response | 39 |
The Paradox of Alcohol and Sleep: Initial Sedation and Subsequent Sleep Disruption | 42 |
The Relationship Between Sleep and Life Expectancy | 44 |
Pineal Gland | 47 |
Melatonin Secretion | 48 |
Other Effects of Melatonin | 51 |
Physiology of Sleep | 53 |
Rapid Sleep (REM) and Slow Sleep | 62 |
Sleep Stages | 66 |
Dreams | 70 |
Hypothalamic Control of Sleep and Circadian Rhythm | 75 |
Risk Factors of Sleep Disorders | 82 |
Causes of Insomnia | 92 |
CHAPTER II: SLEEP DISTURBANCES | 97 |
Classification | 97 |
International Classification of Diseases (ICD) | 97 |
Diagnostic and Statistical Manual of Mental Disorders (DSM) | 100 |
International Classification of Sleep Disorders (ICSD) | 102 |
Common Types of Sleeping Disorders | 106 |
Insomnia | 106 |
Hypersomnia | 107 |
Parasomnias | 113 |
Apnea or Hypopnea in Sleep | 116 |
Insomnia | 121 |
Diagnosis of Sleep Disorders | 126 |
CHAPTER III: BIOLOGICAL APPROACH | 139 |
Brain Tissue Cells, Types, and Their Function | 141 |
Advantages and Challenges of Different Cell Types | 166 |
Neural Stem Cells | 175 |
Targeted Precursor Stem Cells | 184 |
Mesenchymal Stem Cells | 185 |
Key Characteristics and Potential Benefits of Mesenchymal Stem Cells | 186 |
Therapeutic Insights and Challenges | 188 |
Induced Pluripotent Stem Cells | 189 |
Embryonic Stem Cells | 198 |
Precursor Stem Cells Definition and Function | 200 |
Neural Stem Cells in Sleep Regulation | 205 |
The Role of the Hypothalamus Cells | 209 |
The Role of the Thalamus Cells | 215 |
The Role of the Brainstem Cells | 219 |
The Role of the Cerebral Cortex Cells | 223 |
The Role of the Cerebellum Cells | 226 |
The Role of the Amygdala Cells | 228 |
The Role of the Hippocampus Cells | 232 |
The Role of Pineal Gland Cells | 237 |
The Role of the Spinal Cord Cells | 239 |
The Brain Structures Responsible for Rapid Sleep | 242 |
The Structures Responsible for Slow Sleep | 245 |
The Role of Mitochondria and Mito-organelles in CNS | 257 |
Mitochondrial Functions Relevant to Sleep Regulation | 259 |
Mitochondrial Dysfunction in Sleep Disorders | 260 |
Benefits of Mitochondrial-Targeted Approach | 260 |
Stem Cell Therapy and Mitochondrial Transfer | 261 |
Neural Nano Peptides | 265 |
Role of Pineal Gland Peptides | 266 |
Neural Peptides and Sleep Regulation | 268 |
CHAPTER IV: PHYSIOTHERAPY | 271 |
Continuous Positive Airway Pressure (CPAP) Therapy | 271 |
Transcranial Electrostimulation | 276 |
Magnesium and Bromide Electrophoresis | 279 |
Aeroionotherapy | 281 |
Electrobiosleep | 283 |
Phototherapy | 285 |
Darsonvalization | 287 |
Holistic Integrative Approach | 289 |
Nutrition and Diet | 292 |
Cognitive Behavioral Therapy for Insomnia (CBTI) | 297 |
BIBLIOGRAPHY | 301 |
Additional information
Weight | N/A |
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Select Book Type | Printed English (Paperback), eBook English |
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