REWRITING CELULAR DESTINY: Prof. Mike Chan on Reversing Age in Over 400 Human Cell Types

KOTA KINABALU, Sabah, July 28, 2025 — In the world of regenerative medicine, few voices carry the authority, experience, and scientific clarity of Prof. Dr. Mike Chan, founder of European Wellness Biomedical Group. Known for pioneering brain- and organ-specific stem cell therapies, Prof. Chan now reveals deeper insight into a game-changing approach: reversing biological age in all 400+ distinct cell types across the human body’s 78 organs.

One Genome, Many Destinies

“All 400+ cell types in the body share the same DNA,” Prof. Chan explains. “But they differ dramatically in how that DNA is expressed.”

What makes one cell a liver hepatocyte and another a neuron? According to Prof. Chan, it lies in the epigenetic language of the body:

Key Cellular Mechanisms Behind Precision Regeneration

• DNA methylation: Chemical tags that regulate gene activity without altering DNA itself.

Why it matters? These switches help determine a cell’s function and behavior.

• Glycation patterns: Sugar molecules binding to proteins or DNA, causing cellular stress.

Why it matters? Linked to accelerated aging and degenerative disease.

• mRNA profiles: Messenger RNA shows which genes are actively producing proteins.

Why it matters? Reveals what each cell is building and doing in real time.

• Transcription factors: Proteins that activate or suppress genes within the cell.

Why it matters? Crucial for shaping cell identity and directing repair.

This intricate coding system decides each cell’s function, aging process, and regenerative potential — a concept that forms the foundation of his precision bioregenerative therapy model.

Human and Animal Similarities — But With a Twist

Prof. Chan notes that humans and animals share many biological cell structures — nuclei, mitochondria, ribosomes — and use DNA and proteins for genetic instruction. “In the fetal stage, the 400+ stem cells of mammals, including humans, are almost indistinguishable,” he says. “But what sets us apart is how these cells specialize as we grow. That’s where biohacking can make the difference.”

Biohacking Age — One Cell Type at a Time

“We are not just managing symptoms,” Prof. Chan emphasizes. “We are biohacking aging itself.”

By precisely targeting the 400+ stem and parenchymal cell types of each organ, including the brain — Prof. Chan and his team are developing therapies to reverse biological age at the cellular level. This goes far beyond the multipotent stem cell research that dominates much of the global field.

“Others focus mostly on tissue-based multipotent stem cells, which we also work with,” he says. “But our exceptional advantage lies in applying organ-specific precursor and progenitor stem cells — something no one else does at this scale.”

Healing With Precision: Like Treats Like

Inspired by the classical principle “Similia Similibus Curantur” — like treats like — Prof. Chan’s protocols use cell-type matching therapies to achieve superior results. Each therapy is tailored to the exact cell type of the affected tissue or organ:

• Hepatocyte stem cells for liver regeneration
• Retinal, optic nerve & occipital lobe cells for glaucoma, macular degeneration, and retinitis pigmentosa
• Islets of Langerhans for diabetes type 1 and 2
• Cardiomyocytes for heart regeneration
• Renal precursor cells for kidney rejuvenation
• Frontal lobe cells for Alzheimer’s
• Substantia nigra cells for Parkinson’s
• Pineal gland cells for sleep disorders
• Pulmonary cells for respiratory support

This hyper-targeted approach enables true regeneration, not just temporary repair.

The Future: Cell-Specific Longevity

Prof. Chan believes that longevity medicine must go beyond superficial biomarkers and tackle aging at the cellular root. “We don’t just reverse aging in the skin or joints, we go inside the body’s control systems, organ by organ, cell by cell,” he says.

As science advances and cell mapping becomes more refined, his philosophy becomes increasingly validated. “The future belongs to those who treat not just symptoms, but the cellular code behind every disease,” he adds.