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Holistic advances for Parkinson’s Disease

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Holistic Advances for Parkinson’s Disease: The Comprehensive Management with Biological Approach, Personalized Cellular Perspectives, Mitochondrial, and Neural Peptides Benefits offers an integrative and forward-thinking perspective on the management of Parkinson’s disease (PD), uniting decades of scientific discovery with emerging biological therapies. This book delves deep into the multifactorial nature of PD, presenting a personalized roadmap that includes cellular regenerative strategies, mitochondrial support, and the therapeutic potential of neural and bioactive peptides.

Written for clinicians, researchers, and informed patients, it explores innovative pathways that go beyond symptom control—addressing the root biological dysfunctions that drive disease progression. From cellular modulation and neuroplasticity enhancement to autonomic balance and mitochondrial optimization, this book offers a truly comprehensive and holistic vision for improving outcomes and restoring quality of life in those affected by Parkinson’s Disease.

Holistic Advances for Parkinson’s Disease is a transformative resource for anyone seeking to understand and implement the next generation of Parkinson’s care.

SKU: 9781662965289 Categories: ,

Description

Authors
Prof. Dr. Mike K.S. Chan and Dr. Dina Tulina

Published by
EUROPEAN WELLNESS ACADEMY – Medical Research

Medical Research
ISBN: 9781662965289
eISBN: 9781662965296
Library of Congress Control Number: 2025940634

DOI: https://doi.org/10.69669/wj3242

Author Bio:

Professor Dato’ Sri Dr. Mike K.S. Chan is a pioneer of Cellular and Cell Membrane Therapy in Europe and Asia since the early 1980’s. He founded one of the world’s largest researchers of Bio-Molecular Medicine based in Switzerland and Germany with a global presence in almost eighty countries. He has conducted more than 1,000 lectures, seminars, and symposiums worldwide in the fields of antiaging, cell regeneration, regenerative medicine, and stem-cell therapies.

Dr. Dina Tulina is a specialist in anti-aging and regenerative medicine with extensive experience in the field. Basing her knowledge on scientific and research experience within the scope of neuropsychiatry (age-related brain changes and associated cognitive and mental disorders), Dr Dina has expanded and enriched her expertise by incorporating preventative medicine, natural and complementary therapies for age-related changes, and the use of biologics in regenerative medicine. Guided by the philosophy “He, who owns the youth, owns the future”, Dr Dina is deeply passionate about the educational aspects of anti-aging medicine and wellness.

Table of Content

 

 

CHAPTER I: ESSENTIAL INSIGHTS ON PARKINSON’S DISEASE
1
Introduction 1
Clinical Appearance 3
In the Young 4
In the Elderly 6
In Women 7
In Men 10
Epidemiology of Parkinson’s Disease Worldwide 11
Geographic Distribution of Parkinson’s Disease Cases 11
Projected Growth of PD Cases Worldwide 14
Neuropathology and Causes 16
Genetic Factors in Neurological Disorders: The Role of Heredity in PD 16
Idiopathic Parkinson’s Disease 17
The Genetic Basis of PD 18
Autosomal-Recessive Transmission: A Hidden Threat 19
The Importance of Genetic Screening and Early Detection 19
Other Genetic Factors in PD 20
The Role of Environmental and Lifestyle Factors 20
Induced Parkinsonism by Other Contributing Factors 22
1. Medication-Induced Risks 22
2. Head Injuries and Their Neurological Impact 23
3. The Role of Infections: Viral and Bacterial Encephalitis 24
4. Underlying Medical Conditions as Contributing Factors 24
Symptoms 25
Motor Symptoms of Parkinson’s Disease 26
Non-Motor Symptoms (NMSs) of Parkinson’s Disease 31
1. Cognitive Impairment and Dementia 32
2. Psychiatric Disorders and Emotional Changes 33
3. Sleep Disorders 34
4. Autonomic Nervous System (ANS) Dysfunction 36
5. Sensory Disturbances and Pain 36
6. Fatigue 37
Dystonia and Dyskinesia: Movement-Related Complications 37
Diagnosis 39
Visual Examination by a Neurologist 39
Functional Diagnostic Tests 41
Supplementary Diagnostic Tests 45
Emerging Diagnostic Techniques 48
Emerging Alpha-Synuclein-Based Laboratory Tests 48
Potential Future Diagnostic Methods 49
Stages of Parkinson’s Disease 50
The Five Stages of the Hoehn and Yahr Scale 51
Structure of the MDS-UPDRS 54
CHAPTER II: BIOLOGICAL SCIENCE PERSPECTIVE
57
Traditional Treatment of PD 57
1. Pharmacological (Drug) Treatment 58
2. Surgical Treatment (Deep Brain Stimulation) 60
3. Supportive and Non-Pharmacological Therapies 62
Limitations of Traditional Treatments for PD 63
Brain Tissue Cells, Types, and Their Function 67
Whole Brain 71
Occipital Lobe 72
Frontal Lobe 73
Temporal Lobe 75
Parietal Lobe 78
Thalamus 79
Cerebellum 82
Medulla Oblongata 84
White Matter 87
Hippocampus 87
Amygdala 89
Mesencephalon 92
Rhinencephalon 93
Basal Ganglia 96
Diencephalon 98
Brainstem 99
Cerebral Cortex 103
Cerebral Hemispheres 104
Pineal Gland 106
Biological Approach 107
The Types and Stem Cells’ Function 107
Neural Precursor Cells (NPCs) 111
Targeted Precursor Stem Cells 112
Mesenchymal Stem Cells (MSCs) 114
Induced Pluripotent Stem Cells (iPSCs) 116
Oligodendrocyte Progenitor Cells (OPCs) 117
Embryonic Stem Cells (ESCs) 118
CHAPTER III: CELLULAR STRATEGY FOR PD
121
Neural Precursor Stem Cells (NPCs) 121
The Role of Cellular Approach 123
1. Substantia Nigra (Midbrain) 123
2. Basal Ganglia (Forebrain) 126
3. Striatum (Part of the Basal Ganglia) 127
4. Subthalamic Nucleus/STN (Basal Ganglia) 129
5. Thalamus 130
6. Cortex (Motor Cortex and Prefrontal Cortex) 132
7. Limbic System (Amygdala and Hippocampus) 134
8. Brainstem (Including the Medulla and Pons) 137
9. Cerebellum 141
Mito Organells CNS (MO CNS) Brain 143
The Role of MO CNS Brain in CNS Function 144
The Implications for PD 146
Nano-Size Neuropeptides 149
The Biological Role of Neuropeptides 150
Nano-Size Neuropeptides: A Revolutionary Approach in PD 150
Advanced Physiotherapies in the Management of PD 152
Transcranial Direct Current Stimulation (TDCS) in PD 153
Transcranial Magnetic Stimulation (TMS) in PD 154
Morphogenetic Harmonizer System, Scalar Plasma Wave Modulator 157
Hyperbaric Oxygenation Therapy (HBOT) with Hyperbaric Oxygen Chamber 160
Ozone Therapy 164
REFERENCES
169

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