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Tinnitus and the Brain: Neurobiological Mechanisms and the Emerging Role of Peptide-Based Regenerative Therapy

European Wellness researchers and collaborators have just published a comprehensive review in the Journal of Neurological Sciences and Research – exploring how tinnitus is now understood as a complex brain network disorder, and how peptide-based regenerative therapies may offer a promising new path forward!

Here’s the breakthrough:

Tinnitus affects 10 – 15% of adults globally – yet current treatments only manage symptoms. This paper digs into the real culprits:

✅ Cochlear injury sparking maladaptive brain rewiring

✅ Oxidative stress, mitochondrial dysfunction, and neuroinflammation keeping the “phantom sound” alive

✅ Limbic–auditory network disruptions fueling emotional distress

The potential solution?

Peptide-based biologics – including Mito-Organelles (MO), Nano Organo-Peptides (NOP), and Precursor Stem Cell–derived factors – that can:

✅ Restore cellular energy and calm hyperactive neurons

✅ Rebalance brain circuits and reduce aberrant neural “noise”

✅ Support neuro-regeneration at the source

Tinnitus and the Brain: Neurobiological Mechanisms and the Emerging Role of Peptide-Based Regenerative Therapy

by

Prof. Dr. Mike K.S. Chan, Krista Casazza, Prof. Dr. Michelle B.F. Wong, Dr. Dmytro Klokol and Jonathan R.T. Lakey

Journal of Neurological Sciences and Research; 5(2), 2025
http://doi.org/10.52793/JNSR.2025.5(2)-48

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