Publications

THE HANDBOOK OF SKIN & AGING: THE SCIENCE, PSYCHOLOGY & THERAPY offers a comprehensive and multidisciplinary exploration of one of the most defining aspects of human life: aging. Bridging biological science, psychology, and therapeutic innovation, this volume examines aging not simply as a cosmetic concern, but as a complex process that shapes physical health, emotional well-being, and overall quality of life. Readers are introduced to the core science of aging, including biomarkers, physiological changes, and the evolving understanding of longevity. The book also addresses the psychological and social dimensions of aging, emphasizing identity, purpose, and resilience as central components of healthy aging. With in-depth discussions on skin rejuvenation, anti-aging therapies, and emerging cell-based approaches, it presents both current knowledge and future directions in the field. Designed for clinicians, researchers, students, and informed general readers, this handbook provides a clear, accessible, and authoritative guide to understanding, caring for, and embracing the aging process.

Authors' Bio:

Dr. Glen Alvin is a seasoned medical professional in Dermatology, Aesthetic Medicine, and Regenerative Medicine, with many years of experience in stem cell therapy research. He holds an MD, an Advanced Diploma in Dermatology, and a Master’s in Aesthetic Medicine. Dr. Glen has made significant contributions to his field through numerous publications and lectures at international conferences. His research includes groundbreaking work on cell therapy in Dermatology and Aesthetic Medicine. His ambition is to secure cell therapy a place in mainstream medicine.

Antonio C. Sison, M.D., F, Psychiatry + Dermatology - the first and only board-certified Psychiatrist and board-certified Dermatologist in the Philippines. The reason for this dual residency is his interest in the pursing the field of Psychodermatology. His Clinical Framework is Trauma and how these impacts on patients with psychological and dermatological conditions. Further he is a certified in Eye Movement Desensitization Reprocessing (EMDR) Therapy, this is an effective psychotherapy that neutralized traumatic memories. Moreover, he has Master Certification in Neurolinguistic Programming (NLP). These techniques are useful in addressing cognitions and feelings of the patient. His research focus is on the interplay between Brain and Skin specifically exploring the possible role of EMDR in the improvement of the psychological conditions and dermatological lesions of patients with chronic skin conditions. He is a Retired Associate Professor of the Department of Psychiatry at the University of the Philippines- Philippine General Hospital (UP-PGH). He is a consultant at the Skin and Cancer Foundation Incorporated (SCFI). Past President of the Philippine Psychiatric Association (PPA) for 2022-2023, and presently Treasurer of the Philippine Dermatological Society (2023-2024) and Chair of the Psychodermatology Interest Group of the Philippine Dermatological Society.

Prof. Dato’ Sri Dr. Mike K.S. Chan is a pioneer of Cellular, Organo and Cell Membrane Therapies in Europe and Asia since the early 1980’s. He founded one of the world’s largest research group of Bio-Molecular Medicine based in Switzerland and Germany with a global presence in almost eighty countries. He has conducted more than 1,000 lectures, seminars, and symposiums worldwide in the fields of anti-aging, cell regeneration, bio-regenerative medicine, and stemcell therapies. Author & co-author of numerous books and articles in the fields of cell therapy, immunology, bio-regenerative sciences, nutrition, and innovator of cellular based nutraceuticals & cosmeceuticals, Prof. Mike Chan is also the founder of European Wellness Biomedical Group—an International chain of research and treatment facilities (European Wellness Centers & Retreats) involved in anti-aging, longevity and education (European Wellness Academy). He chairs and also sits on board on numerous prominent anti-aging and cell therapy associations of the world.

About the Article:

The Klotho–FGF23 axis plays a central role in regulating mineral metabolism through the intricate interaction between the kidneys, bones, and parathyroid glands. Disruption of this pathway is now recognised as a key driver in the progression of chronic kidney disease (CKD) and its systemic complications.

This review highlights how imbalance in this endocrine system contributes to:

✔️ Phosphate and vitamin D dysregulation

✔️ Vascular calcification and accelerated ageing processes

✔️ Renal fibrosis and progressive kidney damage

✔️ Increased cardiovascular risk

Importantly, the study also underscores the protective role of Klotho, which exhibits anti-inflammatory, antioxidant, and cytoprotective effects, positioning it as both a biomarker and a promising therapeutic target in kidney disease.

Why It Matters:

Emerging evidence suggests that restoring Klotho levels may offer reno-protective and cardio-protective benefits, opening new possibilities for early diagnosis and targeted treatment strategies in nephrology.

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BIOREGENERATIVE SPORT MEDICINE: Precision Healing & Performance Resilience for Modern Athletes delivers a clear and integrated overview of how the athlete’s body performs, adapts, and recovers across training cycles, competition demands, and the lifespan of athletic participation. Grounded in anatomy, physiology, biomechanics, and exercise science, it translates core scientific principles into practical clinical applications that support informed decision-making in both performance and injury contexts.

The book provides evidence-based guidance on injury evaluation, diagnostic imaging, rehabilitation planning, and return-to-play management, emphasizing risk stratification, load management, and long-term athlete development. Sport-specific chapters on football, athletics, and combat sports outline the distinct mechanical, metabolic, and neurocognitive demands of each discipline, alongside their characteristic injury patterns and targeted strategies for prevention, conditioning, and performance optimization.

Beyond traditional models of care, this book address the evolving landscape of modern sports medicine: bioregenerative sport medicine therapies. Integrating clinical insight with emerging research, the book highlights individualized, data-informed approaches to athlete health that align performance goals with durability and longevity.

Designed for clinicians, physiotherapists, athletic trainers, coaches, and sports science professionals, BIOREGENERATIVE SPORT MEDICINE: Precision Healing & Performance Resilience for Modern Athletes serves as a concise yet authoritative resource that bridges foundational science and applied practice. It equips practitioners with the conceptual frameworks and practical tools needed to optimize athlete health, enhance performance, and support sustainable participation across all levels of sport—from youth development to elite competition.

Prof. Dato’ Sri Dr. Mike K.S. Chan is Founder & Chairman of the European Wellness Biomedical Group and Chief Researcher/Chief Technical & Research Director across its international R&D programs. A pioneer of cellular therapy since the 1980s, he helped introduce stem cell and bioregenerative medicine across Asia, building a global network of clinics and research centers—today a chain of 40+ integrative and regenerative medical clinics with 1,000+ staff. He serves as ESAAM Scientific Committee Head for Regenerative Medicine & Stem Cells and ESAAM Chairman/Director for Asia; Associate Professor (AASCP, USA); Associate Professor (Lincoln University College, Kuala Lumpur); Chairman of the European Wellness Academy; Senator of Germany’s BWA; and Honorary Chief Healthcare Advisor to Swiss Strategic Partners. His portfolio includes multiple international patents in immunotherapy, stem cell transport media, and parenteral formulations, and he is a multi-award recipient in Europe and the Middle East. An active academic collaborator (MIT, Cambridge, USC, UCI, Heidelberg), Prof. Chan has authored/co-authored 60+ books and 170+ scientific publications, and has delivered 1000+ lectures and seminars across 60+ regions on anti-aging, regenerative medicine, peptides, and stem cell therapies.

Authors: Prof. Dr. Mike K.S. Chan, Prof. Dr. Michelle B.F. Wong, Krista Casazza and Jonathan R.T. Lakey
Publisher: Neurology - Research & Surgery; 9(2), 2026
Publisher's URL: https://www.scivisionpub.com/journals/neurology-research-surgery/articles/a-multimodal-regenerative-platform-for-spinal-cord-injury-regionally-specified-neural-progenitor-grafts-synergized-with-mitochondria-targeted-peptides-and-placenta-cns-nano-organopeptidic-biologics

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European Wellness researchers and collaborators have just published a compelling new case study in the Journal of Regenerative Medicine & Biology Research – documenting how a novel biological and botanical topical therapy helped heal severe burns on a child's feet rapidly and without scarring – all without the need for surgery!

📚 Publication Title: Case Study: Accelerated Healing and Instantaneous Pain Relief of Severe Pediatric Plantar Burns Using a Novel Biological and Botanical Topical Therapy (“Ace Schnelle”)
✍️ Authors: Dr. Alaa Abdelkarim, Shirene Amer and Prof. Dr. Mike K.S. Chan
📑 Journal: Journal of Regenerative Medicine & Biology Research; 7(1), 2026

What it’s about:

An 8-year-old girl suffered severe thermal and chemical burns on the soles of both feet – injuries that would normally require surgery, skin grafting, and a long, painful recovery. Instead, the research team applied "Ace Schnelle” – a proprietary topical formulation.

The results?

✅ On the very first application, the child's pain stopped completely
✅ Dead tissue separated naturally on its own – no surgical removal needed
✅ Within just 3 weeks, the wounds had fully healed with normal, healthy skin restored
✅ No scarring

While further clinical studies are needed, the results of this case are truly encouraging – and could point to a simpler, less invasive way to treat severe burns in the future!

Read the full publication here:

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Neuroregeneration and Novel Insights in Borderline Emotional Disorders in Regenerative Medicine explores the “clinical gray zone” where persistent stress, anxiety, low mood, and emotional dysregulation impair daily life without always fitting neat diagnostic categories. Written for clinicians, researchers, and informed readers, it reframes “borderline” states through a dimensional, mechanism-based lens—linking fluctuating symptoms to stress circuits, neuroendocrine signaling, inflammation, metabolic function, mitochondrial bioenergetics, and the gut–brain axis.

Bridging established psychiatric care with emerging biological strategies, the book surveys evidence-informed adjuncts such as neuromodulatory peptides, organoid and mito-organelle research platforms, cellular and glial-focused approaches, and structured physiotherapeutic and lifestyle interventions. Practical in intent and translational in scope, it offers a roadmap for integrating psychosocial treatment with safety-minded, biologically rational tools—aimed at enhancing resilience, restoring homeostasis, and supporting earlier, more personalized intervention before symptoms harden into chronic disorder.

Prof. Dato’ Sri Dr. Mike K.S. Chan is Founder & Chairman of the European Wellness Biomedical Group and Chief Researcher/Chief Technical & Research Director across its international R&D programs. A pioneer of cellular therapy since the 1980s, he helped introduce stem cell and bioregenerative medicine across Asia, building a global network of clinics and research centers—today a chain of 40+ integrative and regenerative medical clinics with 1,000+ staff. He serves as ESAAM Scientific Committee Head for Regenerative Medicine & Stem Cells and ESAAM Chairman/Director for Asia; Associate Professor (AASCP, USA); Associate Professor (Lincoln University College, Kuala Lumpur); Chairman of the European Wellness Academy; Senator of Germany’s BWA; and Honorary Chief Healthcare Advisor to Swiss Strategic Partners. His portfolio includes multiple international patents in immunotherapy, stem cell transport media, and parenteral formulations, and he is a multi-award recipient in Europe and the Middle East. An active academic collaborator (MIT, Cambridge, USC, UCI, Heidelberg), Prof. Chan has authored/co-authored 60+ books and 150+ scientific publications, and has delivered 1000+ lectures and seminars across 60+ regions on anti-aging, regenerative medicine, peptides, and stem cell therapies.

Dr. Dina Tulina is a Medical Advisor and physician specializing in anti-aging, regenerative medicine, and comprehensive wellness. She integrates preventive, biological, and natural care to promote longevity and vitality beyond conventional practice. At European Wellness Global, she contributes to biomedical innovation with holistic approaches and the translation of research into practical applications. Guided by her belief that true health is balance and vitality, and functional longevity, Dr. Tulina is dedicated to shaping the future of personalized and preventive healthcare.

What if metabolic syndrome isn't really about blood sugar and belly fat – but a total communication breakdown inside your cells? 🧬

European Wellness researchers have just published a compelling new review in Neurology – Research & Surgery – exploring how metabolic syndrome may actually be a systems-wide collapse of peptide signaling across your organs, and how regenerative peptide biology could offer a new way to address it at the source!

Here's the big picture:

• The paper reframes Metabolic Syndrome as a coordinated collapse of peptide-governed networks connecting the gut, pancreas, liver, muscles, fat tissue, and mitochondria.
• When these communication lines break down, things such as insulin sensitivity, inflammation, and cellular energy production start falling out of sync.
• This review explores how next-gen peptide therapeutics may help reconnect the network, including Mitochondrial Peptides, Nano Organo-Peptides, Klotho Peptides, Organ-Specific Peptides, and Mito Organelles.

Metabolic syndrome affects nearly 1 in 4 adults worldwide – and conventional treatments often manage symptoms without addressing the deeper biological failures driving the condition.

This review positions regenerative peptide therapeutics as a coherent, systems-level strategy capable of restoring the upstream peptide networks that keep our metabolism balanced, resilient, and healthy.

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Peptides 101: Regenerative Applications in Modern Medicine provides a foundational overview of peptide biology and their expanding therapeutic roles in regenerative and functional medicine. The book reviews peptide structure, synthesis, and signaling pathways, with emphasis on their applications in tissue repair, immune modulation, neuroprotection, and metabolic regulation. Integrating current research with clinical perspectives, it highlights safety profiles, evidence-based protocols, and emerging trends in peptide therapeutics. Designed for clinicians, biomedical researchers, and students, this text bridges basic science and translational medicine to illuminate the regenerative potential of peptide-based interventions.

Unlock the therapeutic power of peptides—nature’s own precision messengers—in this comprehensive introduction to their role in regenerative and integrative medicine. From cellular signaling and tissue repair to neuroprotection and metabolic optimization, Peptides 101 demystifies complex biochemical pathways and translates cutting-edge science into practical medical insight.

Inside, you’ll explore:

• Core principles of peptide biology and receptor signaling; Clinical applications in reversal of chronic diseases and metabolic syndrome, wound healing, longevity and neuroregeneration;
• Evidence-based discussion of safety, dosing, and protocols;
• Future directions in peptide-based therapeutics and personalized medicine.
• Whether you’re a physician, researcher, or student of modern bioregenerative science, this book provides the foundation and framework to understand and apply peptide therapy responsibly and effectively.

Prof. Dato’ Sri Dr. Mike K.S. Chan, Researcher, Author, and Educator, Founder and Chairman of the European Wellness Biomedical Group; Senior Technical Consultant at EWBG; Head of Scientific committee of preventive, regenerative and anti-aging medicine and Asian Chairman (ESAAM); Adjunct Professor of Lincoln University College (Malaysia); Associate Professor of AASCP, USA (American Academy of Stem Cell Physicians), Chairman for A4M, USA (American Academy of Anti-Aging Medicine) for Thailand/Asia, Japan’s Regenerative Medical Association MMJ (Multi-Dimensional Holistic Medical Team Japan) and co-Founder of FCTI Precursor Stem Cells (Europe), Author of over 70 books and over 150 publications, has experience of 45 over years in Stem cells Research in Germany, Switzerland, European Union, Soviets, China, Mexico, USA, Japan, Middle East since early 80’s, presenter for over 10000 presentations and scientific lectures globally at most major conferences of the World on anti-aging and precision medicine. He is also a pioneer in Regenerative Medicine and Cellular Therapies in a big way in the 80’s into Asia Pacific, the Middle East and Australia.

Thomas Skutella, MD, PostDoc (Max Planck Institute for Psychiatry, Munich, Germany), Full Professor at Heidelberg University, former group leader in the Neuroscience Research Center (Charite Berlin, Germany), director of the Center for Regenerative Medicine (Tübingen, Germany), Head of the department of Neuroanatomy in the Institute for Anatomy and Cell Biology (Heidelberg, Germany), Group for Regeneration and Reprogramming, Medical Faculty, Institute for Anatomy and Cell Biology, Heidelberg University (Germany).

Jonathan R.T. Lakey, B.Sc., M.Sc., Ph.D. (University of Alberta at Edmonton, Canada), Professor Emeritus, Department of Surgery, University of California Irvine (CA, USA); Department of Biomedical Engineering, University of California Irvine (CA, USA), Director of Research at the Clinical Islet Program in the Department of Surgery at the University of California, Irvine (CA, USA), Outstanding Leadership in Alberta Science Award from the Alberta Science and Technology Leadership Foundation, the Outstanding Achievement Award from the Canadian Diabetes Association, and Royal College of Physicians and Surgeons.

Olha Nishkumai, MD, PhD, Professor, Doctor of Medical Sciences, Board Certified Specialist Cardiologist, Rheumatologist, and Internal Medicine specialist; Full Professor at the Department of Internal Medicine No. 2 at Bogomolets National Medical University (UA); Medical Consultant at the European Wellness Biomedical Group.

Dmytro Klokol, MD, Specialist in General Surgery (Board Certified, MoH UA), PhD (Emergency and Reconstructive Surgery), GCP (Malaysia, USA), PostDoc (Regenerative Medicine, NL, EU); Certified expert in Interventional procedures in Regenerative Medicine and chronic pain management (Spain, EU); Certified Educator at International Accreditation Organization (IAO, USA); HRDCorp certified educator and trainer (Malaysia); International Board for Anti-aging and Regenerative Medicine (IBARM, USA) certifying academic board member.

Here's What It's About:

This case report follows a 27-year-old patient with severe corneal opacity treated over 90 days using ACE Retino (sublingual and topical peptides) and Cataclear (bioactive eye drops).

Key observations include:

• 92% improvement in corneal clarity
• Significant visual acuity gains
• Reduced stromal edema
• And marked improvements in inflammatory and oxidative biomarkers – all without surgical intervention.

💡 Why This Matters:

Corneal opacity affects millions globally and often requires surgery with associated risks. This preliminary case suggests peptide-based therapies targeting inflammation, oxidative stress, and fibrosis may offer a promising non-invasive alternative – though larger controlled trials are needed.

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European Wellness researchers and collaborators have just published a comprehensive review in the Journal of Neurological Sciences and Research – exploring how tinnitus is now understood as a complex brain network disorder, and how peptide-based regenerative therapies may offer a promising new path forward!

Here's the breakthrough:

Tinnitus affects 10 – 15% of adults globally – yet current treatments only manage symptoms. This paper digs into the real culprits:

✅ Cochlear injury sparking maladaptive brain rewiring

✅ Oxidative stress, mitochondrial dysfunction, and neuroinflammation keeping the "phantom sound" alive

✅ Limbic–auditory network disruptions fueling emotional distress

The potential solution?

Peptide-based biologics – including Mito-Organelles (MO), Nano Organo-Peptides (NOP), and Precursor Stem Cell–derived factors – that can:

✅ Restore cellular energy and calm hyperactive neurons

✅ Rebalance brain circuits and reduce aberrant neural "noise"

✅ Support neuro-regeneration at the source

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