Longevity for the Heart: Strategies Against Cardiac Inflammaging (Stem Cell & Bio-regenerative Approaches)
$61.00 – $122.00
Our planet is getting older… Aging is a natural and inevitable process and part of our lives, but it increases the risk of numerous diseases, one of which is cardiovascular pathology. Despite the successful progress in modern medicine, cardiovascular diseases remain a leading cause of death worldwide. What makes age-related heart disease so difficult to combat? What eludes our understanding of the reasons for this? And why do existing treatments not meet expectations?
One of the root causes is a concealed factor: chronic low-grade inflammation that occurs even without any apparent infection or acute inflammatory stimulus and fuels the aging process within our cells. This phenomenon, known as “InflammAging”, accelerates heart aging and increases vulnerability to disease.
In this book, we tried to look at the problem of cardiac aging from the point of view of internal cellular mechanisms and uncover how innovative bioregenerative therapies can revolutionize the way we prevent and treat and open up new opportunities for extending cardiac longevity. By targeting InflammAging at its core, we aim to unlock a new path to long-term heart health and extended vitality.
Discover the future of heart health within these pages.
Description
Authors
Prof. Dr. Mike K.S. Chan, Dr. Olha Nishkumai, Prof. Dr. Michelle B.F. Wong, Dr. Nataliia Shyshkina, Dr. Margaryta Iemelianova, Halyna Mostbauer, Iuliia Rudenko, Oksana Zaytseva, Oksana Rokyta, Andrii Bezrodnyi
Published by
EUROPEAN WELLNESS ACADEMY
ISBN: 9786176321255
Table of Content
| Foreword | 5 |
| About authors | 7 |
| Abbreviations | 12 |
| Introduction | 14 |
| Chapter 1. The Мain “Еnemies” of Мyocardial Longevity | 17 |
| 1.1. The role of oxidative stress, free radical-induced inflammation, mitochondrial dysfunction and apoptosis in cardiac senescence | 19 |
| 1.2. Inflammation and metabolism violation of the Nicotinamide adenine dinucleotide (NAD) — Sirtuins as one of the cardiac aging mechanisms | 23 |
| 1.3. The role of the inflammasome NLRP3 in the processes of “sterile” inflammation and aging. Genomic instability and epigenetic alterations in cardiac senescence | 27 |
| 1.4. The main vasoregulatory peptides, growth factors and their role in cardiovascular pathology | 31 |
| Chapter 2. Structural and Functional Changes in the Heart in Inflammaging | 39 |
| 2.1. Inflammatory cardiofibrosis. Vascular senescence — atherosclerosis and vascular calcification | 40 |
| 2.2. Age-related Inflammation and Hypertension | 56 |
| 2.3. The role of inflammation in age-related heart rhythm disorders | 59 |
| 2.4. Aging and functional changes of pericardium | 61 |
| 2.5. Inflammation, dysbiosis and CVD | 64 |
| 2.6. Low-grade inflammation and diabetic cardiomyopathy | 66 |
| 2.7. Inflammation and Heart Failure | 68 |
| Chapter 3. Inflammaging in Cardiology: Solutions | 71 |
| 3.1. Smoking’s influence on cardiac longevity | 72 |
| 3.2. Role of the Physical Activities | 73 |
| 3.3. Diet: caloric restriction, fasting impact. Mediterranean diet benefits. The role of dietary antioxidants | 79 |
| 3.4. Conventional medicine’s role in relieving inflammation | 90 |
| 3.5. Bioregenerative approaches in the cardiac inflammaging | 101 |
| 3.5.1. Phosphatidylcholine’s role | 101 |
| 3.5.2. Bempedoic acid. Omega-3 fatty acids | 102 |
| 3.5.3. Gut microbiota components improvement | 104 |
| 3.5.4. Flavonoids | 105 |
| 3.5.5. Polyphenols | 107 |
| 3.5.6. Sirtuins — NAD+ | 108 |
| 3.5.7. Vitamin D and K2 | 110 |
| Chapter 4. Stem Cell Therapy | 113 |
| 4.1. Classifi cation of Stem Cells | 115 |
| 4.2. Main barriers for Stem Cell Therapy in cardiology | 118 |
| 4.3. Overcoming the main barriers of Stem Cell tranplantation | 120 |
| 4.4. The methods of Stem Cell transplantation | 123 |
| Chapter 5. Cell Peptide Therapy in Aging Heart | 125 |
| Chapter 6. Exosomes | 129 |
| Conclusion | 133 |
| References | 134 |
Additional information
| Weight | N/A |
|---|---|
| Select Book Type | Printed English (Paperback), eBook English |
Only logged in customers who have purchased this product may leave a review.
Related products
-
Select options This product has multiple variants. The options may be chosen on the product pageImmunotherapy in Bioregenerative Medicine
$75.00 – $150.00 -
Select options This product has multiple variants. The options may be chosen on the product pageHandbook of Anti-Aging Medicine
$98.00 – $195.00
Reviews
There are no reviews yet.