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Assessment of the Fractures Risk in Patients with Nephrolithiasis

European Wellness researchers and collaborators have just published an important new study in SSP Modern Pharmacy and Medicine – revealing a hidden link between kidney stone disease and bone health that standard bone density tests might miss!

Here’s What It’s About:

✅ The research team studied 80 patients to understand how kidney stone disease (nephrolithiasis) affects fracture risk

✅ Standard bone mineral density (BMD) tests showed no difference between patients with and without kidney stones

✅ However, the Trabecular Bone Score (TBS) – which measures bone quality and microarchitecture – was significantly lower in kidney stone patients

✅ When TBS was factored into the 10-year fracture risk calculation, patients with kidney stones showed a notably higher risk of fractures

This means traditional bone density scans alone may not tell the full story for people with kidney stone disease.

💡 Why This Matters:

Kidney disease can disrupt vitamin D metabolism and trigger secondary hyperparathyroidism – a double threat that affects both stone formation and bone integrity. By incorporating TBS into fracture risk assessments, clinicians can identify at-risk patients earlier and begin preventive therapy sooner – potentially avoiding life-altering fractures down the road.

Assessment of the Fractures Risk in Patients with Nephrolithiasis

by

Oleg Nikitin, Illia Kordubailo, Dr. Olha Nishkumay. Prof. Dr. Mike K.S. Chan, Prof. Dr. Michelle B.F. Wong, Dr. Dmytro Klokol, Oksana Zaytseva and Hennadii Reznikov

SSP Modern Pharmacy & Medicine; 5(4), 2025
https://doi.org/10.53933/0waq5n36

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