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Stem Cells: Novel Opportunities for Patients with Diabetes

Diabetes remains a global health challenge, often requiring lifelong management. But what if we could go beyond managing symptoms and explore pathways to functional treatment?

Some key insights…

✅ Pluripotent Stem Cells (hPSCs/iPSCs): These remarkable cells hold the potential to be transformed into insulin-producing beta cells, offering a path towards replacing lost function and potentially achieving insulin independence. Early trials are showing encouraging results!

✅ Mesenchymal Stem Cells (MSCs): Allogeneic MSCs show promise in protecting existing beta cells and modulating the immune system, potentially slowing disease progression and improving transplant outcomes.

✅ Overcoming Hurdles: While challenges like immune rejection and costs exist, researchers are actively developing strategies like immune evasion techniques and bioengineered scaffolds to enhance the safety and effectiveness of these therapies.

Stem Cells: Novel Opportunities for Patients with Diabetes

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Prof. Dr. Mike K.S. Chan, Jonathan R.T. Lakey, Carolina Bluguermann, Krista Casazza, Adrian Mutto, Bradley Robinson, Zijiang Yang, Ivan Lopez Vitolas, Ian Jenkins, Waldemar Lernhardt and Pedro Gutiérrez Castrellón

American Journal of Biomedical Science & Research; 26(4), 2025
https://biomedgrid.com/pdf/AJBSR.MS.ID.003454.pdf

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