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The Kidney Paradox: Bioregenerative and Longevity Approaches for Chronic Renal Disorders

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The Kidney Paradox: Bioregenerative and Longevity Approaches for Chronic Renal Disorders presents a transformative view of kidney health by reframing the organ as a dynamic, interconnected system rather than an isolated unit. Drawing on systems biology, omics sciences, and clinical insights, the book explores how renal function emerges from complex interactions between molecular pathways, cellular processes, and whole-body physiology. It challenges traditional reductionist approaches, revealing that kidney-related diseases arise not only from localized injury but from widespread disruptions across biological networks.

From foundational physiology to emerging regenerative therapies, the text navigates the kidney’s role in maintaining homeostasis, its susceptibility to environmental and lifestyle influences, and the paradoxical nature of chronic renal disorders. It highlights advances in stem cell research, tissue engineering, gene editing, and artificial intelligence, offering a forward-looking vision of precision nephrology and preventive care. Designed for clinicians, researchers, and health professionals, this book ultimately redefines kidney disease as a modifiable, system-wide condition and emphasizes a holistic approach centred on integration, restoration, and long-term wellness.

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SKU: 9781662980992 Categories: ,

Description

Authors
Mike K.S. Chan and Glen Alvin

Other author/Contributor

Samsidar Anwar, Mohd Iskandar Jumat, Nurul Wahidah Jamil, Siti Azmah Jambo

Published by
EUROPEAN WELLNESS ACADEMY – Medical Research

ISBN: 9781662980992 eISBN: 9781662981005

Library of Congress Control Number: 2026951837

DOI: https://doi.org/10.69669/ri3101

Authors Bio:

Professor Dato’ Sri Dr. Mike K.S. Chan is Founder & Chairman of the European Wellness Biomedical Group and Chief Researcher/Chief Technical & Research Director across its international R&D programmes. A pioneer of cellular therapy since the 1980s, he helped introduce stem cell and bioregenerative medicine across Asia, building a global network of clinics and research centres—today a chain of 40+ integrative and regenerative medical clinics with 1,000+ staff. He serves as ESAAM Scientific Committee Head for Regenerative Medicine & Stem Cells and ESAAM Chairman/Director for Asia; Associate Professor (AASCP, USA); Associate Professor (Lincoln University College, Kuala Lumpur); Chairman of the European Wellness Academy; Senator of Germany’s BWA; and Honorary Chief Healthcare Advisor to Swiss Strategic Partners. His portfolio includes multiple international patents in immunotherapy, stem cell transport media, and parenteral formulations, and he is a multi-award recipient in Europe and the Middle East. An active academic collaborator (MIT, Cambridge, USC, UCI, Heidelberg), Professor Chan has authored/co-authored 70+ books and 180+ scientific publications, and has delivered 1000+ lectures and seminars across 60+ regions on anti-aging, regenerative medicine, peptides, and stem cell therapies.

Table of Content

List of Abbreviations vii
Preface xi
PART I: THE FOUNDATION: UNDERSTANDING KIDNEY PHYSIOLOGY
Chapter 1: The Kidney in Health: A Systems Overview 3
Chapter 2: The Molecular Language Of Renal Health 21
Chapter 3: Environmental and Lifestyle Determinants 51
PART II: THE MEDICAL ISSUES: COMMON RENAL DISORDERS AND THEIR SYSTEMIC COMPLICATIONS
Chapter 4: The Spectrum Of Acute Kidney Injury (AKI) 73
Chapter 5: The Spectrum of Chronic Kidney Disease (CKD) 117
Chapter 6: The Spectrum of Diabetic Nephropathy (DN) 157
PART III: THE REGENERATIVE SOLUTIONS: BIOREGENERATIVE AND CELLULAR THERAPIES FOR RENAL HEALTH
Chapter 7: Stem Cell Therapy: Regenerating The Injured Kidney 193
Chapter 8: Exosomes: Precision Signalling for Renal Regeneration 231
Chapter 9: Peptides: Molecular Strategies for Renal Repair and Longevity 249
PART IV: THE FUTURE: SYSTEMS MEDICINE AND PREVENTIVE PARADIGMS
Chapter 10: Precision Nephrology and Predictive Analytics 271
Chapter 11: The Wellness Perspective 297
Chapter 12: From Paradox to Paradigm 325

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