Klotho, Obesity, and Inflammation: A Triad of Metabolic Regulation

💡 What’s it about?
This insightful review explores the Klotho protein, often dubbed the “anti-aging gene”, and its intricate relationship with obesity and chronic inflammation—two of the most critical health issues facing modern society.

The article dives into:
✔️ How Klotho acts as a metabolic guardian, regulating insulin sensitivity and energy balance
✔️ The vicious cycle between obesity and systemic inflammation
✔️ How low Klotho expression may accelerate metabolic dysfunction and age-related diseases
✔️ The potential for targeting the Klotho pathway in developing new therapeutic approaches for obesity, diabetes, and chronic inflammatory conditions

By understanding this molecular triad, researchers and clinicians can uncover promising directions for regenerative medicine, longevity science, and metabolic health interventions.

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