Authors: Prof. Dr. Mike K.S. Chan, Krista Casazza, Prof. Dr. Michelle B.F. Wong, Dr. Dmytro…
Peptide Therapy in Animal Reproductive Health: Advances, Mechanisms, and Translational Perspectives
About the Article:
Reproductive health is critical to the welfare, performance, and sustainability of animal populations, from companion animals to livestock and equines. Traditional reproductive management strategies often focus on hormonal modulation or assisted reproductive technologies, which can improve breeding efficiency but may not address the underlying cellular, endocrine, and metabolic dysfunctions that contribute to infertility and sub‑fertility in animals.
This comprehensive review synthesizes the latest evidence on peptide‑based therapies and organ‑derived biologics as next‑generation tools in animal reproductive care. Peptide therapeutics, whether synthetic, stem‑cell secretome‑derived, or organ extract‑based offer targeted modulation of:
- Endocrine balance and steroidogenesis
- Mitochondrial bioenergetics and oxidative homeostasis
- Angiogenesis and tissue repair by modulating key reproductive and regenerative pathways
Peptide Therapy in Animal Reproductive Health: Advances, Mechanisms, and Translational Perspectives
by
Prof. Dr. Mike K.S. Chan, Prof. Dr. Michelle B.F. Wong, Krista Casazza, Dr. Dmytro Klokol and Jonathan R.T. Lakey
Journal of Stem Cell Research; 7(1), 2025
https://doi.org/10.52793/JSCR.2026.7(1)-80
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